Chemical Formula: C8H13NO4
Chemical Formula C8H13NO4
Found 50 metabolite its formula value is C8H13NO4
2-Keto-6-acetamidocaproate
2-Keto-6-acetamidocaproate is an intermediate in lysine degradation. It can be generated from N6-acetyl-L-lysine. N-acetyl-lysine is an acetylated amino acid. Post-translational lysine-acetylation is one of two major modifications of lysine residues in various proteins. Acetylation of specific lysine residues in the N-terminal domains of core histones is a biochemical marker of active genes. Acetylation is now known to play a major role in eukaryotic transcription. Specifically, acetyltransferase enzymes that act on particular lysine side chains of histones and other proteins are intimately involved in transcriptional activation. N6-acetyl-L-lysine can be converted to 2-Keto-6-acetamidocaproate via the enzyme N6-acetyllysine aminotransferase and then 2-keto-6-acetamidocaproate can be reduced enzymatically to 5-acetamidovalerate. [HMDB] 2-Keto-6-acetamidocaproate is an intermediate in lysine degradation. It can be generated from N6-acetyl-L-lysine. N-acetyl-lysine is an acetylated amino acid. Post-translational lysine-acetylation is one of two major modifications of lysine residues in various proteins. Acetylation of specific lysine residues in the N-terminal domains of core histones is a biochemical marker of active genes. Acetylation is now known to play a major role in eukaryotic transcription. Specifically, acetyltransferase enzymes that act on particular lysine side chains of histones and other proteins are intimately involved in transcriptional activation. N6-acetyl-L-lysine can be converted to 2-Keto-6-acetamidocaproate via the enzyme N6-acetyllysine aminotransferase and then 2-keto-6-acetamidocaproate can be reduced enzymatically to 5-acetamidovalerate.
(3R)-3-Hydroxy-N-[(3S)-2-oxooxolan-3-yl]butanamide
1-(1-Hydroxyethyl)-4-isocyano-4-cyclopentene-1,2,3-triol
(2R,5S)-5-(METHOXYCARBONYL)PIPERIDINE-2-CARBOXYLIC ACID
1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid
2-Methyl-2-propanyl 2-(hydroxyimino)-3-oxobutanoate
(3R)-3-Hydroxy-N-[(3S)-2-oxooxolan-3-yl]butanamide
(2S,5S)-5-(2-carboxyethyl)pyrrolidine-2-carboxylic acid
6-acetamido-2-oxohexanoic acid
A member of the class of acetamides that is the acetyl derivative of 6-amino-2-oxohexanoic acid.
