Chemical Formula: C85H116F3N19O15
Chemical Formula C85H116F3N19O15
Found 1 metabolite its formula value is C85H116F3N19O15
Targefrin
Targefrin
C85H116F3N19O15 (1699.8849942000002)
Targefrin is a potent EphA2-targeting agent, acts as an antagonist. Targefrin binds EphA2-LBD with 21 nM dissociation constant and an IC50 value of 10.8 nM. Targefrin induces cellular receptor internalization and degradation in several pancreatic cancer cell lines[1].