Chemical Formula: C75H109BrN18O22S

Microspinosamide

C75H109BrN18O22S (1724.6867514)

A cyclodepsipeptide isolated from the marine sponge Sidonops microspinosa and has been shown to exhibit anti-HIV-1 activity.

[(3r,6r,7s,10s,13r,18as)-7-{[(2s)-2-{[(2s)-2-{[(2r)-2-{[(2s)-2-{[(2r)-2-({[(2s)-1-[3-(4-bromophenyl)-3-hydroxy-2-{[(2r)-1-hydroxy-2-[(hydroxymethylidene)amino]propylidene]amino}propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3,3-dimethylbutylidene]amino}-1-hydroxy-3,3-dimethylpentylidene]amino}-1-hydroxy-3-(1h-indol-3-yl)propylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-1-hydroxy-3-sulfopropylidene]amino}-1,11-dihydroxy-10-[2-(c-hydroxycarbonimidoyl)ethyl]-13-isopropyl-6,9-dimethyl-4,8,14-trioxo-3h,6h,7h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-f]1-oxa-4,7,10,13-tetraazacyclohexadecan-3-yl]acetic acid

C75H109BrN18O22S (1724.6867514)

(7-{[2-({2-[(2-{[2-({2-[({1-[3-(4-bromophenyl)-3-hydroxy-2-({1-hydroxy-2-[(hydroxymethylidene)amino]propylidene}amino)propanoyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-1-hydroxy-3,3-dimethylbutylidene}amino)-1-hydroxy-3,3-dimethylpentylidene]amino}-1-hydroxy-3-(1h-indol-3-yl)propylidene)amino]-5-carbamimidamido-1-hydroxypentylidene}amino)-1-hydroxy-3-sulfopropylidene]amino}-1,11-dihydroxy-10-[2-(c-hydroxycarbonimidoyl)ethyl]-13-isopropyl-6,9-dimethyl-4,8,14-trioxo-3h,6h,7h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-f]1-oxa-4,7,10,13-tetraazacyclohexadecan-3-yl)acetic acid

C75H109BrN18O22S (1724.6867514)

[(3r,6r,7r,10s,13r,18as)-7-{[(2s)-2-{[(2s)-2-{[(2r)-2-{[(2r)-2-{[(2s)-2-({[(2s)-1-[3-(4-bromophenyl)-3-hydroxy-2-{[(2r)-1-hydroxy-2-[(hydroxymethylidene)amino]propylidene]amino}propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3,3-dimethylbutylidene]amino}-1-hydroxy-3,3-dimethylpentylidene]amino}-1-hydroxy-3-(1h-indol-3-yl)propylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-1-hydroxy-3-sulfopropylidene]amino}-1,11-dihydroxy-10-[2-(c-hydroxycarbonimidoyl)ethyl]-13-isopropyl-6,9-dimethyl-4,8,14-trioxo-3h,6h,7h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-f]1-oxa-4,7,10,13-tetraazacyclohexadecan-3-yl]acetic acid

C75H109BrN18O22S (1724.6867514)

[(3s,6s,7s,10r,13r,18ar)-7-{[(2r)-2-{[(2r)-2-{[(2s)-2-{[(2s)-2-{[(2s)-2-({[(2s)-1-[3-(4-bromophenyl)-3-hydroxy-2-({1-hydroxy-2-[(hydroxymethylidene)amino]propylidene}amino)propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3,3-dimethylbutylidene]amino}-1-hydroxy-3,3-dimethylpentylidene]amino}-1-hydroxy-3-(1h-indol-3-yl)propylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-1-hydroxy-3-sulfopropylidene]amino}-1,11-dihydroxy-10-[2-(c-hydroxycarbonimidoyl)ethyl]-13-isopropyl-6,9-dimethyl-4,8,14-trioxo-3h,6h,7h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-f]1-oxa-4,7,10,13-tetraazacyclohexadecan-3-yl]acetic acid

C75H109BrN18O22S (1724.6867514)

[(3r,6r,7s,10s,13r,18as)-7-{[(2s)-2-{[(2s)-2-{[(2r)-2-{[(2s)-2-{[(2r)-2-({[(2s)-1-[(2r,3r)-3-(4-bromophenyl)-3-hydroxy-2-{[(2r)-1-hydroxy-2-[(hydroxymethylidene)amino]propylidene]amino}propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3,3-dimethylbutylidene]amino}-1-hydroxy-3,3-dimethylpentylidene]amino}-1-hydroxy-3-(1h-indol-3-yl)propylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-1-hydroxy-3-sulfopropylidene]amino}-1,11-dihydroxy-10-[2-(c-hydroxycarbonimidoyl)ethyl]-13-isopropyl-6,9-dimethyl-4,8,14-trioxo-3h,6h,7h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-f]1-oxa-4,7,10,13-tetraazacyclohexadecan-3-yl]acetic acid

C75H109BrN18O22S (1724.6867514)