Chemical Formula: C6H11O9P
Chemical Formula C6H11O9P
Found 54 metabolite its formula value is C6H11O9P
6-Phosphonoglucono-D-lactone
6-phosphonoglucono-d-lactone, also known as D-glucono-1,5-lactone 6-phosphate or 6-pgdl, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. 6-phosphonoglucono-d-lactone is soluble (in water) and a moderately acidic compound (based on its pKa). 6-phosphonoglucono-d-lactone can be found in a number of food items such as chicory leaves, pepper (c. chinense), opium poppy, and green bell pepper, which makes 6-phosphonoglucono-d-lactone a potential biomarker for the consumption of these food products. 6-phosphonoglucono-d-lactone can be found primarily in cellular cytoplasm. 6-phosphonoglucono-d-lactone exists in all living species, ranging from bacteria to humans. In humans, 6-phosphonoglucono-d-lactone is involved in warburg effect, which is a metabolic disorder. 6-phosphoglucono-delta-lactone (d-6PGL) is the immediate product of the Glucose-6-phosphate dehydrogenase (G-6-PD), the first enzyme of the hexose monophosphate pathway. (PMID 3711719). The pentose-phosphate pathway provides reductive power and nucleotide precursors to the cell through oxidative and nonoxidative branches. 6-Phosphogluconolactonase is the second enzyme of the oxidative branch and catalyzes the hydrolysis of 6-phosphogluconolactones, the products of glucose 6-phosphate oxidation by glucose-6-phosphate dehydrogenase. By efficiently catalyzing the hydrolysis of d-6PGL, 6-phosphogluconolactonase prevents the reaction between d-6PGL and intracellular nucleophiles; such a reaction would interrupt the functioning of the pentose-phosphate pathway. (PMID 11457850).
2-Keto-3-deoxy-6-phosphogluconic acid
2-Keto-3-deoxy-6-phosphogluconic acid is a substrate for Fructose-bisphosphate aldolase A. It can be found in Achromobacter, Alcaligenes, Clostridium and Rhodobacteraceae (PMID: 5383859; PMID: 5304016) (M. Szymona and M. Doudoroff. Carbohydrate Metabolism in Rhodopseudomonas spheroides. J. Gen. Microbiol (1960). 22: 167-183). 2-Keto-3-deoxy-6-phosphogluconic acid is a substrate for Fructose-bisphosphate aldolase A. [HMDB]
6-O-phosphonato-D-glucono-1,5-lactone(2-)
6-O-phosphonato-D-glucono-1,5-lactone(2-) is also known as 6-phosphonoglucono-delta-Lactone or 6-PGDL. 6-O-phosphonato-D-glucono-1,5-lactone(2-) is considered to be soluble (in water) and acidic
D-fructose 6-phosphate
D-fructose 6-phosphate is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. D-fructose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). D-fructose 6-phosphate can be found in a number of food items such as roselle, cashew nut, red bell pepper, and cucumber, which makes D-fructose 6-phosphate a potential biomarker for the consumption of these food products.
alpha-D-glucose 6-phosphate
Mannose 6-phosphate, also known as mannose 6-phosphoric acid, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Mannose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). Mannose 6-phosphate can be found in a number of food items such as japanese chestnut, rubus (blackberry, raspberry), allium (onion), and nanking cherry, which makes mannose 6-phosphate a potential biomarker for the consumption of these food products. Mannose 6-phosphate may be a unique E.coli metabolite. The M6P-tagged lysosomal enzymes are shipped to the late endosomes via vesicular transport. Enzyme replacement therapy (ERT) for several lysosomal storage diseases relies on this pathway to efficiently direct synthetic enzymes to the lysosome where each can metabolize its particular substrate. The pH in the late endosome can reach 6.0, which causes dissociation of M6P from its receptor. Upon release, the enzymes are ferried to their final destination in the lysosomes. The MPRs are packed into vesicles that bud off the late endosome and return to the "trans"-Golgi network. In this way, the MPRs can be recycle.
alpha-D-glucose 6-phosphate
Mannose 6-phosphate, also known as mannose 6-phosphoric acid, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Mannose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). Mannose 6-phosphate can be found in a number of food items such as japanese chestnut, rubus (blackberry, raspberry), allium (onion), and nanking cherry, which makes mannose 6-phosphate a potential biomarker for the consumption of these food products. Mannose 6-phosphate may be a unique E.coli metabolite. The M6P-tagged lysosomal enzymes are shipped to the late endosomes via vesicular transport. Enzyme replacement therapy (ERT) for several lysosomal storage diseases relies on this pathway to efficiently direct synthetic enzymes to the lysosome where each can metabolize its particular substrate. The pH in the late endosome can reach 6.0, which causes dissociation of M6P from its receptor. Upon release, the enzymes are ferried to their final destination in the lysosomes. The MPRs are packed into vesicles that bud off the late endosome and return to the "trans"-Golgi network. In this way, the MPRs can be recycled . Mannose 6-phosphate, also known as mannose 6-phosphoric acid, is a member of the class of compounds known as hexose phosphates. Hexose phosphates are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Mannose 6-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). Mannose 6-phosphate can be found in a number of food items such as japanese chestnut, rubus (blackberry, raspberry), allium (onion), and nanking cherry, which makes mannose 6-phosphate a potential biomarker for the consumption of these food products. Mannose 6-phosphate may be a unique E.coli metabolite. The M6P-tagged lysosomal enzymes are shipped to the late endosomes via vesicular transport. Enzyme replacement therapy (ERT) for several lysosomal storage diseases relies on this pathway to efficiently direct synthetic enzymes to the lysosome where each can metabolize its particular substrate. The pH in the late endosome can reach 6.0, which causes dissociation of M6P from its receptor. Upon release, the enzymes are ferried to their final destination in the lysosomes. The MPRs are packed into vesicles that bud off the late endosome and return to the "trans"-Golgi network. In this way, the MPRs can be recycle.
[(3S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-oxooxan-2-yl] dihydrogen phosphate
[(2R,3R,4S,5R)-3,4,5-trihydroxy-6-oxooxan-2-yl]methyl dihydrogen phosphate
D-glucopyranose 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of D-glucopyranose 1-phosphate arising from deprotonation of both phosphate OH groups.
alpha-D-glucose 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of alpha-D-glucose 1-phosphate, obtained by deprotonation of the phosphate OH groups.
D-fructose 6-phosphate(2-)
An organophosphate oxoanion arising from deprotonation of both phosphate OH groups of D-fructose 6-phosphate.
beta-D-glucose 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of beta-D-glucose 1-phosphate arising from deprotonation of both phosphate OH groups.
D-tagatofuranose 6-phosphate(2-)
An organophosphate oxoanion that is the dianion of D-tagatofuranose 6-phosphate.
1D-myo-inositol 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of 1D-myo-inositol 1-phosphate.
keto-D-tagatose 6-phosphate(2-)
An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of keto-D-tagatose 6-phosphate; major species at pH 7.3.
aldehydo-D-galactose 6-phosphate(2-)
An doubly-charged organophosphate oxoanion arising from deprotonation of the phosphate OH groups of aldehydo-D-galactose 6-phosphate; major species at pH 7.3.
D-fructofuranose 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of D-fructofuranose 1-phosphate.
D-fructofuranose 6-phosphate(2-)
An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of D-fructofuranose 6-phosphate; major species at pH 7.3.
D-galactopyranose 6-phosphate(2-)
A D-glucopyranose 6-phosphate(2-) resulting from deprotonation of the phosphate OH groups of D-galactopyranose 6-phosphate; major species at pH 7.3.
alpha-L-galactose 1-phosphate(2-)
Dianion of alpha-L-galactose 1-phosphate arising from deprotonation of the phosphate OH groups; major species at pH 7.3.
L-tagatofuranose 6-phosphate(2-)
An organophosphate oxoanion that is the dianion of L-tagatofuranose 6-phosphate arising from deprotonation of both OH groups of the phosphate.
1D-myo-inositol 3-phosphate(2-)
The dianion of 1D-myo-inositol 3-phosphate.
alpha-D-mannose 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of alpha-D-mannose 1-phosphate.
1D-myo-inositol 4-phosphate(2-)
Dianion of 1D-myo-inositol 4-phosphate.
D-mannopyranose 6-phosphate(2-)
A D-hexopyranose 6-phosphate(2-) that is the dianion of D-mannopyranose 6-phosphate arising from deprotonation of the phosphate function.
1D-myo-inositol 6-phosphate(2-)
A organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of 1D-myo-inositol 6-phosphate.
keto-L-tagatose 6-phosphate(2-)
An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of keto-L-tagatose 6-phosphate; major species at pH 7.3.
alpha-D-mannose 6-phosphate(2-)
Dianion of alpha-D-mannose 6-phosphate; major species at pH 7.3.
L-sorbose 1-phosphate(2-)
An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of L-sorbose 1-phosphate. Major microspecies at pH 7.3
alpha-D-glucose 6-phosphate(2-)
A D-glucopyranose 6-phosphate(2-) obtaned by deprotonation of the phosphate OH groups of alpha-D-glucose 6-phosphate; major species at pH 7.3.
beta-D-glucose 6-phosphate(2-)
A doubly-charged organophosphate oxoanion arising from deprotonation of the phosphate OH groups of beta-D-glucose 6-phosphate; major species at pH 7.3.
2-Dehydro-3-deoxy-6-phospho-D-gluconic acid
The 5-phospho derivative of 2-dehydro-D-gluconic acid.
beta-D-fructofuranose 6-phosphate(2-)
An organophosphate oxoanion that is the dianion of beta-D-fructofuranose 6-phosphate arising from deprotonation of the phosphate OH groups.
aldehydo-D-glucose 6-phosphate(2-)
Dianion of aldehydo-D-glucose 6-phosphate arising from deprotonation of the two OH groups of the phosphate.
L-galactose 1-phosphate(2-)
An organophosphate oxoanion that is the dianion of L-galactose 1-phosphate arising from deprotonation of both OH groups of the phosphate.
6-O-phosphono-D-glucono-1,5-lactone
An aldonolactone phosphate comprising D-glucono-1,5-lactone having the phosphate group at the 6-position.
D-glucopyranose 6-phosphate(2-)
An organophosphate oxoanion resulting from deprotonation of the phosphate OH groups of D-glucopyranose 6-phosphate; major species at pH 7.3.
D-allose 6-phosphate(2-)
An organophosphate oxoanion arising from deprotonation of the phosphate OH groups of D-allose 6-phosphate; major species at pH 7.3.
alpha-D-galactose 1-phosphate(2-)
An organophosphate oxoanion arising from deprotonation of the phosphate OH groups of alpha-D-galactose 1-phosphate; major species at pH 7.3.
beta-D-fructofuranose 1-phosphate(2-)
a D-fructofuranose 1-phosphate(2-) obtained by deprotonation of the phosphate OH groups of beta-D-fructofuranose 1-phosphate; major species at pH 7.3.
beta-L-galactose 1-phosphate(2-)
A L-galactose 1-phosphate(2-) in which the anomeric center has beta-configuration.