Chemical Formula: C63H113N11O12

Chemical Formula C63H113N11O12

Found 20 metabolite its formula value is C63H113N11O12

Alisporivir

25,30-diethyl-33-(1-hydroxy-2-methylhex-4-en-1-yl)-1,4,7,10,12,15,19,27,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21,24-tris(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone

C63H113N11O12 (1215.857)


   

Cyclosporin G

33-(1-hydroxy-2-methylhex-4-en-1-yl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone

C63H113N11O12 (1215.857)


   

Cyclosporin D

33-(1-hydroxy-2-methylhex-4-en-1-yl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21,30-tris(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone

C63H113N11O12 (1215.857)


   
   
   
   
   

Val2-Cyclosporine

Val2-Cyclosporine

C63H113N11O12 (1215.857)


Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A[1][2]. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc)[3]. Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A[1][2]. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc)[3].

   

Alisporivir

Alisporivir

C63H113N11O12 (1215.857)


D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents > D003524 - Cyclosporins COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C254 - Anti-Infective Agent > C281 - Antiviral Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Alisporivir (Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.

   

8,11,14,17,20,23,26,29,32-Undecone

8,11,14,17,20,23,26,29,32-Undecone

C63H113N11O12 (1215.857)


D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents > D003524 - Cyclosporins

   

33-[(E)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

33-[(E)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

C63H113N11O12 (1215.857)


   

US9090657, Debio-025, 2

US9090657, Debio-025, 2

C63H113N11O12 (1215.857)


   

(3s,6s,9s,12r,15s,18s,21s,24s,30s,33s)-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

(3s,6s,9s,12r,15s,18s,21s,24s,30s,33s)-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhex-4-en-1-yl)-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-21,30-dipropyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhex-4-en-1-yl)-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-21,30-dipropyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

14,17,23,32-tetrahydroxy-33-[(4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

14,17,23,32-tetrahydroxy-33-[(4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhex-4-en-1-yl)-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhex-4-en-1-yl)-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

(3r,6s,9s,12r,15s,18s,21s,24s,30s,33s)-15,30-diethyl-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

(3r,6s,9s,12r,15s,18s,21s,24s,30s,33s)-15,30-diethyl-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

15,30-diethyl-14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhex-4-en-1-yl)-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

15,30-diethyl-14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhex-4-en-1-yl)-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

(3s,6s,9r,12r,15s,18s,21s,24s,30s,33s)-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-21,30-dipropyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

(3s,6s,9r,12r,15s,18s,21s,24s,30s,33s)-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-21,30-dipropyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)


   

(3s,6s,9s,12r,15s,18s,21s,24s,30s)-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21,30-triisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

(3s,6s,9s,12r,15s,18s,21s,24s,30s)-14,17,23,32-tetrahydroxy-33-[(1r,2r,4e)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21,30-triisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptone

C63H113N11O12 (1215.857)