Chemical Formula: C50H65F3IN7O6S

Chemical Formula C50H65F3IN7O6S

Found 1 metabolite its formula value is C50H65F3IN7O6S

MS432

MS432 is a first-in-class and highly selective PD0325901-based von Hippel-Lindau-recruiting PROTAC degrader for MEK1 and MEK2. MS432 displays good plasma exposure in mice, exhibiting DC50 values of 31 nM and 17 nM for MEK1, MEK2 in HT29 cells respectively[1].