Chemical Formula: C45H47NO18

Chemical Formula C45H47NO18

Found 2 metabolite its formula value is C45H47NO18

6a, 3'-p-Dihydroxypaclitaxel

4,12-bis(acetyloxy)-1,8,9,17,17-pentahydroxy-15-{[2-hydroxy-3-(4-hydroxyphenyl)-3-(phenylformamido)propanoyl]oxy}-10,14-dimethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate

C45H47NO18 (889.2793)


6a, 3-p-Dihydroxypaclitaxel is a metabolite of paclitaxel. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a U.S. National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it taxol. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to paclitaxel and the BMS compound is sold under the trademark Taxol. (Wikipedia)

   

6a, 3-p-Dihydroxypaclitaxel

6a, 3-p-Dihydroxypaclitaxel

C45H47NO18 (889.2793)