Chemical Formula: C41H66N7O18P3S

(3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-CoA, also known as 3(S)-hydroxy-all-cis-8,11,14,17-eicosatetraenoyl-CoA, belongs to the class of organic compounds known as long-chain fatty acyl CoAs. These are acyl CoAs where the group acylated to the coenzyme A moiety is a long aliphatic chain of 13 to 21 carbon atoms. (3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-CoA is considered to be a practically insoluble (in water) and relatively neutral molecule.

(5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5z,8s,9e,11z,14z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5Z_8S_9E_11Z_14Z)-8-hydroxyicosa-5_9_11_14-tetraenoic acid thioester of coenzyme A. (5z,8s,9e,11z,14z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-coa is an acyl-CoA with 20 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5z,8s,9e,11z,14z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5z,8s,9e,11z,14z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA into (5Z_8S_9E_11Z_14Z)-8-hydroxyicosa-5_9_11_14-tetraenoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5Z_8S_9E_11Z_14Z)-8-hydroxyicosa-5_9_11_14-tetraenoylcarnitine is converted back to (5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA occurs in four steps. First, since (5Z,8S,9E,11Z,14Z)-...

(5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5z,8z,10e,12s,14z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5Z_8Z_10E_12S_14Z)-12-hydroxyicosa-5_8_10_14-tetraenoic acid thioester of coenzyme A. (5z,8z,10e,12s,14z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-coa is an acyl-CoA with 20 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5z,8z,10e,12s,14z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5z,8z,10e,12s,14z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA into (5Z_8Z_10E_12S_14Z)-12-hydroxyicosa-5_8_10_14-tetraenoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5Z_8Z_10E_12S_14Z)-12-hydroxyicosa-5_8_10_14-tetraenoylcarnitine is converted back to (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA occurs in four steps. First, s...

(5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5e,7z,11z,14z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5E_7Z_11Z_14Z)-9-hydroxyicosa-5_7_11_14-tetraenoic acid thioester of coenzyme A. (5e,7z,11z,14z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-coa is an acyl-CoA with 20 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5e,7z,11z,14z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5e,7z,11z,14z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA into (5E_7Z_11Z_14Z)-9-hydroxyicosa-5_7_11_14-tetraenoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5E_7Z_11Z_14Z)-9-hydroxyicosa-5_7_11_14-tetraenoylcarnitine is converted back to (5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA occurs in four steps. First, since (5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA...

(5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5z,8z,11z,14z)-3-icosa-5,8,11,14-tetraenoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5Z_8Z_11Z_14Z)-3-hydroxyicosa-5_8_11_14-tetraenoic acid thioester of coenzyme A. (5z,8z,11z,14z)-3-icosa-5,8,11,14-tetraenoyl-coa is an acyl-CoA with 20 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5z,8z,11z,14z)-3-icosa-5,8,11,14-tetraenoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5z,8z,11z,14z)-3-icosa-5,8,11,14-tetraenoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA into (5Z_8Z_11Z_14Z)-3-Icosa-5_8_11_14-tetraenoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5Z_8Z_11Z_14Z)-3-Icosa-5_8_11_14-tetraenoylcarnitine is converted back to (5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA occurs in four steps. First, since (5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenas...

(10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(10e)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (10E)-11-(3_4-dimethyl-5-propylfuran-2-yl)undec-10-enoic acid thioester of coenzyme A. (10e)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-coa is an acyl-CoA with 15 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (10e)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (10e)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA into (10E)-11-(3_4-dimethyl-5-propylfuran-2-yl)undec-10-enoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (10E)-11-(3_4-dimethyl-5-propylfuran-2-yl)undec-10-enoylcarnitine is converted back to (10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA occurs in four steps. First, s...

11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

11-{3,4-dimethyl-5-[(1e)-prop-1-en-1-yl]furan-2-yl}undecanoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is an 11-{3_4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoic acid thioester of coenzyme A. 11-{3,4-dimethyl-5-[(1e)-prop-1-en-1-yl]furan-2-yl}undecanoyl-coa is an acyl-CoA with 17 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 11-{3,4-dimethyl-5-[(1e)-prop-1-en-1-yl]furan-2-yl}undecanoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 11-{3,4-dimethyl-5-[(1e)-prop-1-en-1-yl]furan-2-yl}undecanoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA into 11-{3_4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 11-{3_4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoylcarnitine is converted back to 11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 11-{3,4-dimethyl-5-[(1E)-prop-1-en-...

(5Z,8Z)-10-[(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5z,8z)-10-[(2s,3r)-3-[(2z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5Z_8Z)-10-[(2S_3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5_8-dienoic acid thioester of coenzyme A. (5z,8z)-10-[(2s,3r)-3-[(2z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-coa is an acyl-CoA with 20 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5z,8z)-10-[(2s,3r)-3-[(2z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5z,8z)-10-[(2s,3r)-3-[(2z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5Z,8Z)-10-[(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5Z,8Z)-10-[(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5Z,8Z)-10-[(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-CoA into (5Z_8Z)-10-[(2S_3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5_8-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5Z_8Z)-10-[(2S_3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5_8-dienoylcarnitine is converted back to (5Z,8Z)-10-[(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-CoA ...

3-oxodihomo gamma-linolenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

A 3-oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (11Z,14Z,17Z)-3-oxoicosatrienoic acid.

(3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoic acid.

CoA 20:4;O

C41H66N7O18P3S (1069.3397726000003)

(3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5Z,8Z,11Z,14Z)-3-Icosa-5,8,11,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5E,7Z,11Z,14Z)-9-hydroxyicosa-5,7,11,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5Z,8S,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(10E)-11-(3,4-dimethyl-5-propylfuran-2-yl)undec-10-enoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

(5Z,8Z)-10-[(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl]deca-5,8-dienoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

5,6-EET-CoA

C41H66N7O18P3S (1069.3397726000003)

8,9-EET-CoA

C41H66N7O18P3S (1069.3397726000003)

14,15-EET-CoA

C41H66N7O18P3S (1069.3397726000003)

11,12-EET-CoA

C41H66N7O18P3S (1069.3397726000003)

15-HETE-CoA

C41H66N7O18P3S (1069.3397726000003)

5-HETE-CoA

C41H66N7O18P3S (1069.3397726000003)

12-HETE-CoA

C41H66N7O18P3S (1069.3397726000003)

S-[2-[3-[[4-[[[(5S)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (8Z,11Z,14Z,17Z)-3-hydroxyicosa-8,11,14,17-tetraenethioate

C41H66N7O18P3S (1069.3397726000003)

(8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoic acid.

(9Z,12Z,15Z)-3-oxoicosatrienoyl-CoA

C41H66N7O18P3S (1069.3397726000003)

A 3-oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (9Z,12Z,15Z)-3-oxoicosatrienoic acid

(11Z)-3-oxoicosa-11-enoyl-CoA(4-)

C41H66N7O18P3S (1069.3397726000003)

A 3-oxo-fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate functions of 3-oxo-(11Z)-eicosa-11-enoyl-CoA.

(13Z)-3-oxoicosenoyl-CoA(4-)

C41H66N7O18P3S (1069.3397726000003)

A 3-oxo-fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (13Z)-3-oxoicosenoyl-CoA; major species at pH 7.3.

(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA(4-)

C41H66N7O18P3S (1069.3397726000003)

A 3-hydroxy fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA; major species at pH 7.3.