Chemical Formula: C37H44ClNO6
Chemical Formula C37H44ClNO6
Found 15 metabolite its formula value is C37H44ClNO6
penitrem A
NCGC00163403-03_C37H44ClNO6_(2R,3S,3aR,4aS,4bS,6aR,7S,7dR,8S,9aR,14bS,14cR,16aS)-12-Chloro-2-isopropenyl-14b,14c,17,17-tetramethyl-10-methylene-3,3a,6,6a,7,8,9,9a,10,11,14,14b,14c,15,16,16a-hexadecahydro-2H,4bH-7,8-(epoxymethano)cyclobuta[5,6]benzo[1,2-e]oxireno[4,4a]chromeno[5,6:6,7]indeno[1,2-b]indole-3,4b,7d(5H)-triol
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins CONFIDENCE Reference Standard (Level 1) Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2].
Pennigritrem
(1S,2R,5S,6S,8R,9S,12S,14S,17R,18S,27R,29S,30R)-23-chloro-11,11,17,18,35,35-hexamethyl-26-methylidene-7,10,13,34-tetraoxa-20-azaundecacyclo[27.4.2.02,18.05,17.06,8.06,14.09,12.019,33.021,32.024,31.027,30]pentatriaconta-19(33),21,23,31-tetraene-5,30-diol
penitrem A
21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2].
C37H44ClNO6_(2aS,2bR,3aS,3bS,6S,6dR,7S,8aR,13bS,13cR,15aS,16aS)-11-Chloro-1,1,13b,13c,17,17-hexamethyl-9-methylene-1,2a,2b,5,5a,6,7,8,8a,9,10,13,13b,13c,14,15,15a,16a-octadecahydro-3bH-6,7-(epoxymethano)cyclobuta[5,6]benzo[1,2-e]oxeto[3,2:2,3]oxireno[4,4a]chromeno[5,6:6,7]indeno[1,2-b]indole-3b,6d(4H)-diol
NCGC00380694-01_C37H44ClNO6_(2aS,2bR,3aS,3bS,6S,6dR,7S,8aR,13bS,13cR,15aS,16aS)-11-Chloro-1,1,13b,13c,17,17-hexamethyl-9-methylene-1,2a,2b,5,5a,6,7,8,8a,9,10,13,13b,13c,14,15,15a,16a-octadecahydro-3bH-6,7-(epoxymethano)cyclobuta[5,6]benzo[1,2-e]oxeto[3,2:2,3]oxireno[4,4a]chromeno[5,6:6,7]indeno[1,2-b]indole-3b,6d(4H)-diol
(1S,2R,5S,6S,8R,9S,12S,14S,17R,18S,27R,29S,30R)-23-chloro-11,11,17,18,35,35-hexamethyl-26-methylidene-7,10,13,34-tetraoxa-20-azaundecacyclo[27.4.2.02,18.05,17.06,8.06,14.09,12.019,33.021,32.024,31.027,30]pentatriaconta-19(33),21,23,31-tetraene-5,30-diol
(1S,2R,5S,6S,8R,9S,12S,14S,17R,18S,27R,29S,30R)-23-chloro-11,11,17,18,35,35-hexamethyl-26-methylidene-7,10,13,34-tetraoxa-20-azaundecacyclo[27.4.2.02,18.05,17.06,8.06,14.09,12.019,33.021,32.024,31.027,30]pentatriaconta-19(33),21,23,31-tetraene-5,30-diol
(2s,3r,6s,8r,9s,10r,12r,13s,21s,22r,24r)-28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
(2s,3r,6s,8r,9s,10r,12r,13s,21s,22r,24r)-28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
(2s,3r,6s,8r,9s,10r,12s,13s,21r,22r,24r)-28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
(2s,3r,6s,8r,9s,10r,12s,13s,21r,22r,24r)-28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
(1s,2r,5s,6s,8r,9s,12s,14s,17r,18s,27r,29s,30r)-23-chloro-11,11,17,18,35,35-hexamethyl-26-methylidene-7,10,13,34-tetraoxa-20-azaundecacyclo[27.4.2.0²,¹⁸.0⁵,¹⁷.0⁶,⁸.0⁶,¹⁴.0⁹,¹².0¹⁹,³³.0²¹,³².0²⁴,³¹.0²⁷,³⁰]pentatriaconta-19(33),21,23,31-tetraene-5,30-diol
(1s,2r,5s,6s,8r,9s,12s,14s,17r,18s,27r,29s,30r)-23-chloro-11,11,17,18,35,35-hexamethyl-26-methylidene-7,10,13,34-tetraoxa-20-azaundecacyclo[27.4.2.0²,¹⁸.0⁵,¹⁷.0⁶,⁸.0⁶,¹⁴.0⁹,¹².0¹⁹,³³.0²¹,³².0²⁴,³¹.0²⁷,³⁰]pentatriaconta-19(33),21,23,31-tetraene-5,30-diol
(2s,3r,6s,8r,9s,10s,12r,13s,22r,24r)-28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
(2s,3r,6s,8r,9s,10s,12r,13s,22r,24r)-28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
28-chloro-22-(2-hydroxypropan-2-yl)-2,3-dimethyl-25-methylidene-8-(prop-1-en-2-yl)-7,11-dioxa-31-azanonacyclo[16.13.0.0²,¹⁶.0³,¹³.0⁶,¹².0¹⁰,¹².0¹⁹,³⁰.0²⁰,²⁷.0²¹,²⁴]hentriaconta-1(18),16,19,27,29-pentaene-9,13,21-triol
(1s,2r,5s,6s,8r,9s,10r,12s,15r,16s,25r,27s,28r)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1s,2r,5s,6s,8r,9s,10r,12s,15r,16s,25r,27s,28r)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1r,2s,5r,6r,8s,9r,10s,12r,15s,16r,25s,27r,28s)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1r,2s,5r,6r,8s,9r,10s,12r,15s,16r,25s,27r,28s)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1r,2s,5r,6s,8r,9r,10s,12r,15s,16r,25s,27r,28s)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1r,2s,5r,6s,8r,9r,10s,12r,15s,16r,25s,27r,28s)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1s,2r,5s,6r,8s,9s,10r,12s,15r,16s,25r,27s,28r)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
(1s,2r,5s,6r,8s,9s,10r,12s,15r,16s,25r,27s,28r)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
