Chemical Formula: C35H60N7O17P3S
Chemical Formula C35H60N7O17P3S
Found 29 metabolite its formula value is C35H60N7O17P3S
(2E)-Tetradecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
(2E)-Tetradecenoyl-CoA is an intermediate in fatty acid metabolism, the substrate of the enzymes acyl-CoA oxidase and Oxidoreductases [EC 1.3.3.6-1.3.99.-] and enzymes acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase [EC 1.3.99.3-1.3.99.13]; (2E)-Tetradecenoyl-CoA is an intermediate in fatty acid elongation in mitochondria, being the substrate of the enzyme trans-2-enoyl-CoA reductase (NADPH) [EC 1.3.1.38]. (KEGG) [HMDB] (2E)-Tetradecenoyl-CoA is an intermediate in fatty acid metabolism, the substrate of the enzymes acyl-CoA oxidase and Oxidoreductases [EC 1.3.3.6-1.3.99.-] and enzymes acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase [EC 1.3.99.3-1.3.99.13]; (2E)-Tetradecenoyl-CoA is an intermediate in fatty acid elongation in mitochondria, being the substrate of the enzyme trans-2-enoyl-CoA reductase (NADPH) [EC 1.3.1.38]. (KEGG).
(2S,6R,10R)-Trimethyl-2E-hendecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
(2S,6R,10R)-trimethyl-2E-hendecenoyl-CoA is an acyl-CoA with (2S,6R,10R)-trimethyl-2E-hendecenoate moiety. Acyl-CoA (or formyl-CoA) is a coenzyme involved in the metabolism of fatty acids. It is a temporary compound formed when coenzyme A (CoA) attaches to the end of a long-chain fatty acid inside living cells. The compound undergoes beta oxidation, forming one or more molecules of acetyl-CoA. This, in turn, enters the citric acid cycle, eventually forming several molecules of ATP. (2S,6R,10R)-trimethyl-2E-hendecenoyl-CoA is an acy-CoA with (2S,6R,10R)-trimethyl-2E-hendecenoate moiety.
5Z-tetradecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
5Z-tetradecenoyl-CoA is also known as 14:1(N-9)-CoA or (cis-Delta(5))-Tetradecanoyl-CoA. 5Z-tetradecenoyl-CoA is considered to be slightly soluble (in water) and acidic. 5Z-tetradecenoyl-CoA is a fatty ester lipid molecule
Myristoleoyl-CoA
C35H60N7O17P3S (975.2979100000001)
Myristoleoyl-CoA, also known as (9Z)-myristoleoyl-coenzyme A or (Z)-tetradec-9-enoyl-CoA, is a member of the class of compounds known as long-chain fatty acyl-CoAs. Long-chain fatty acyl-CoAs are acyl-CoAs where the group acylated to the coenzyme A moiety is a long aliphatic chain of 13 to 21 carbon atoms. Thus, myristoleoyl-CoA is considered to be a fatty ester lipid molecule. Myristoleoyl-CoA results from the formal condensation of the thiol group of coenzyme A with the carboxy group of myristoleic acid.
(4Z)-tetradec-4-enoyl-CoA
C35H60N7O17P3S (975.2979100000001)
(4z)-tetradec-4-enoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (4Z)-tetradec-4-enoic acid thioester of coenzyme A. (4z)-tetradec-4-enoyl-coa is an acyl-CoA with 14 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (4z)-tetradec-4-enoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (4z)-tetradec-4-enoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (4Z)-tetradec-4-enoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (4Z)-tetradec-4-enoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (4Z)-tetradec-4-enoyl-CoA into (4Z)-tetradec-4-enoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (4Z)-tetradec-4-enoylcarnitine is converted back to (4Z)-tetradec-4-enoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (4Z)-tetradec-4-enoyl-CoA occurs in four steps. First, since (4Z)-tetradec-4-enoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (4Z)-tetradec-4-enoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, Enoyl-CoA hydrase catalyzes the addition of water across the newly formed double bond to make an alcohol. Third, 3-hydroxyacyl-C...
(7Z)-tetradec-7-enoyl-CoA
C35H60N7O17P3S (975.2979100000001)
(7z)-tetradec-7-enoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (7Z)-tetradec-7-enoic acid thioester of coenzyme A. (7z)-tetradec-7-enoyl-coa is an acyl-CoA with 8 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (7z)-tetradec-7-enoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (7z)-tetradec-7-enoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (7Z)-tetradec-7-enoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (7Z)-tetradec-7-enoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (7Z)-tetradec-7-enoyl-CoA into (7Z)-tetradec-7-enoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (7Z)-tetradec-7-enoylcarnitine is converted back to (7Z)-tetradec-7-enoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (7Z)-tetradec-7-enoyl-CoA occurs in four steps. First, since (7Z)-tetradec-7-enoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (7Z)-tetradec-7-enoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, Enoyl-CoA hydrase catalyzes the addition of water across the newly formed double bond to make an alcohol. Third, 3-hydr...
CoA 14:1
C35H60N7O17P3S (975.2979100000001)
(5E)-tetradecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (5E)-tetradecenoic acid.
(2E)-Tetradecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
(2E)-Tetradecenoyl-CoA is an intermediate in fatty acid metabolism, the substrate of the enzymes acyl-CoA oxidase and Oxidoreductases [EC 1.3.3.6-1.3.99.-] and enzymes acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase [EC 1.3.99.3-1.3.99.13]; (2E)-Tetradecenoyl-CoA is an intermediate in fatty acid elongation in mitochondria, being the substrate of the enzyme trans-2-enoyl-CoA reductase (NADPH) [EC 1.3.1.38]. (KEGG) [HMDB] (2E)-Tetradecenoyl-CoA is an intermediate in fatty acid metabolism, the substrate of the enzymes acyl-CoA oxidase and Oxidoreductases [EC 1.3.3.6-1.3.99.-] and enzymes acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase [EC 1.3.99.3-1.3.99.13]; (2E)-Tetradecenoyl-CoA is an intermediate in fatty acid elongation in mitochondria, being the substrate of the enzyme trans-2-enoyl-CoA reductase (NADPH) [EC 1.3.1.38]. (KEGG).
(3E)-tetradecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (3E)-tetradecenoic acid.
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] tetradec-7-enethioate
C35H60N7O17P3S (975.2979100000001)
(2S,6R,10R)-Trimethyl-2E-hendecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] (E)-tetradec-3-enethioate
C35H60N7O17P3S (975.2979100000001)
Tetradecenoyl-CoA; (Acyl-CoA); [M+H]+
C35H60N7O17P3S (975.2979100000001)
(11Z)-Tetradecenoyl-CoA; (Acyl-CoA); [M+H]+
C35H60N7O17P3S (975.2979100000001)
cis-tetradec-11-enoyl-CoA
C35H60N7O17P3S (975.2979100000001)
A Delta(11)-acyl-CoA having cis-tetradec-11-enoyl as the S-acyl group.
trans-tetradec-11-enoyl-CoA
C35H60N7O17P3S (975.2979100000001)
A Delta(11)-acyl-CoA having trans-tetradec-11-enoyl as the S-acyl group.
(9Z)-myristoleoyl-CoA
C35H60N7O17P3S (975.2979100000001)
An unsaturated fatty acyl-CoA resulting from the formal condensation of the thiol group of coenzyme A with the carboxy group of (9Z)-myristoleic acid.
(5Z)-tetradecenoyl-CoA
C35H60N7O17P3S (975.2979100000001)
An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (5Z)-tetradecenoic acid.
cis-tetradec-3-enoyl-CoA
C35H60N7O17P3S (975.2979100000001)
A tetradecenoyl-CoA having cis-tetradec-3-enoyl as the S-acyl group.