Chemical Formula: C32H35ClFN7O2

Chemical Formula C32H35ClFN7O2

Found 1 metabolite its formula value is C32H35ClFN7O2

Adagrasib

Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. Adagrasib covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP-bound conformation, and inhibits KRAS-dependent signal transduction[1][2].