Chemical Formula: C32H27Cl2F4N3O6

Chemical Formula C32H27Cl2F4N3O6

Found 1 metabolite its formula value is C32H27Cl2F4N3O6

MI-1061 (TFA)

MI-1061 (TFA)

C32H27Cl2F4N3O6 (695.1213)


MI-1061 TFA is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 TFA potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].