Chemical Formula: C31H37F3N8O11

Chemical Formula C31H37F3N8O11

Found 1 metabolite its formula value is C31H37F3N8O11

ADH-6 (TFA)

ADH-6 (TFA)

C31H37F3N8O11 (754.2533768000001)


ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases[1].