Chemical Formula: C31H22N2O2

Chemical Formula C31H22N2O2

Found 1 metabolite its formula value is C31H22N2O2

SIRT6 activator 12q

SIRT6 activator 12q

C31H22N2O2 (454.1681192)


SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity[1].