Chemical Formula: C30H49N3O10S

Chemical Formula C30H49N3O10S

Found 13 metabolite its formula value is C30H49N3O10S

S-(PGA1)-glutathione

7-[(2R)-3-{[(2R)-2-{[(4S)-4-amino-4-carboxy-1-hydroxybutylidene]amino}-2-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl]sulphanyl}-2-[(1E)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid

C30H49N3O10S (643.3138494000001)

S-(PGA1)-glutathione is the gluthathione conjugate of prostaglanding A1. This conjugate is a substrate for MRP2 (31). PGA1 was observed to be able to inhibit. MRP2-mediated transport of DNP-SG quite well. S-(PGA1)-glutathione is the gluthathione conjugate of prostaglanding A1. This conjugate is a substrate for MRP2 (31). PGA1 was observed to be able to inhibit

S-(11-OH-9-deoxy-delta9,12-PGD2)-glutathione

(5Z)-7-[(1S,2E)-5-{[(2R)-2-{[(4R)-4-amino-4-carboxy-1-hydroxybutylidene]amino}-2-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl]sulphanyl}-3-hydroxy-2-[(3S)-3-hydroxyoctylidene]cyclopentyl]hept-5-enoic acid

C30H49N3O10S (643.3138494000001)

S-(11-OH-9-deoxy-delta9,12-PGD2)-glutathione is the glutathione conjugate of S-(11-OH-9-deoxy-delta9,12-PGD2) [HMDB] S-(11-OH-9-deoxy-delta9,12-PGD2)-glutathione is the glutathione conjugate of S-(11-OH-9-deoxy-delta9,12-PGD2).

S-(9-deoxy-delta12-PGD2)-glutathione

(5Z)-7-[(1R,2R)-2-[(3S)-1-{[(2S)-2-{[(4R)-4-amino-4-carboxy-1-hydroxybutylidene]amino}-2-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl]sulphanyl}-3-hydroxyoctyl]-3-oxocyclopentyl]hept-5-enoic acid

C30H49N3O10S (643.3138494000001)

S-(9-hydroxy-PGA1)-glutathione is the glutathione conjugate of S-(9-deoxy-delta12-PGD2) [HMDB] S-(9-hydroxy-PGA1)-glutathione is the glutathione conjugate of S-(9-deoxy-delta12-PGD2).

S-(9-hydroxy-PGA2)-glutathione

(5Z)-7-[(1R,2S)-3-{[(2S)-2-{[(4R)-4-amino-4-carboxy-1-hydroxybutylidene]amino}-2-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl]sulphanyl}-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]hept-5-enoic acid

C30H49N3O10S (643.3138494000001)

S-(9-hydroxy-PGA2)-glutathione is the glutathione conjugate of S-(9-hydroxy-PGA2). Inside L1210 cells, PGA2 was initially conjugated to glutathione and then reduced at the 9-keto position to form 9-OH-PGA2-GSH. The 9-OH-PGA2-GSH was then secreted from the cells and apparently degraded to form the CysGly and Cys derivatives. Intracellular glutathione was decreased markedly by the addition of the PGA2 in L1210 and L929 cells. This result confirms that conjugation of PGA2 to glutathione occurs in both cell types. Formation of the 9-OH-PGA2-GSH and other glutathione-related conjugates was prevented when glutathione was depleted by growth in buthionine sulfoximine. The glutathione-depleted cells were insensitive to the cytotoxicity of the PGA2, suggesting that one of the glutathione-related conjugates may be involved in the cytotoxicity of PGA2. These results end the controversy over the metabolism of PGA2 and suggest mechanisms for its antiviral and antigrowth actions. S-(9-hydroxy-PGA2)-glutathione is the glutathione conjugate of S-(9-hydroxy-PGA2)

10,11-Dihydro-12R-hydroxy-leukotriene C4

(5S,6R,7E,9E,12S,14Z)-6-{[(2R)-2-{[(4R)-4-amino-4-carboxy-1-hydroxybutylidene]amino}-2-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl]sulfanyl}-5,12-dihydroxyicosa-7,9,14-trienoic acid

C30H49N3O10S (643.3138494000001)

This compound belongs to the family of Leukotrienes. These are eicosanoids containing an hydroxyl group attached to the aliphati chain of an arachidonic acid.

11S,15S-dihydroxy-14R-(S-glutathionyl)-5Z,8Z,12E-eicosatrienoic acid

(8Z,11S,12E,14R,15S)-14-{[(2R)-2-{[(4S)-4-amino-4-carboxy-1-hydroxybutylidene]amino}-2-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl]sulphanyl}-11,15-dihydroxyicosa-5,8,12-trienoic acid

C30H49N3O10S (643.3138494000001)

11S,15S-dihydroxy-14R-(S-glutathionyl)-5Z,8Z,12E-eicosatrienoic acid is classified as a member of the Oligopeptides. Oligopeptides are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds. 11S,15S-dihydroxy-14R-(S-glutathionyl)-5Z,8Z,12E-eicosatrienoic acid is considered to be practically insoluble (in water) and acidic. 11S,15S-dihydroxy-14R-(S-glutathionyl)-5Z,8Z,12E-eicosatrienoic acid is an eicosanoid lipid molecule

Chemical Formula: C30H49N3O10S