Chemical Formula: C28H37FN4O4S
Chemical Formula C28H37FN4O4S
Found 1 metabolite its formula value is C28H37FN4O4S
VHL-IN-1
VHL-IN-1
VHL-IN-1 (compound 30) is a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor (dissociation constant Kd=37 nM) that stabilizes and induces HIF-1α transcriptional activity. VHL-IN-1 has potential as a HIF-1α stabilizer and degrader of proteolytically targeted chimeras (PROTACs)[1].