Chemical Formula: C28H28N2

Chemical Formula C28H28N2

Found 2 metabolite its formula value is C28H28N2

N,N'-Dibenzhydrylethane-1,2-diamine

(diphenylmethyl)({2-[(diphenylmethyl)amino]ethyl})amine

C28H28N2 (392.2252368)


AMN082 free base, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 free base potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 free base shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].

   

AMN082 free base

N,N-Dibenzhydrylethane-1,2-diamine

C28H28N2 (392.2252368)


AMN082 free base, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 free base potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 free base shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].