Chemical Formula: C27H48O4
Chemical Formula C27H48O4
Found 139 metabolite its formula value is C27H48O4
27-Deoxy-5b-cyprinol
27-Deoxy-5b-cyprinol is an intermediate in Bile acid synthesis pathway, in a sequence of reactions catalyzed by sterol 27-hydroxylase (CYP27) in the oxidation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,27-tetrol into 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid (PMID: 8496170). 5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol 3-glucuronide, a metabolite of 27-Deoxy-5b-cyprinol, is the major bile alcohol component in serum from cerebrotendinous xanthomatosis patients (PMID: 7920441). 27-Deoxy-5b-cyprinol is an intermediate in Bile acid synthesis pathway, in a sequence of reactions catalyzed by sterol 27-hydroxylase (CYP27) in the oxidation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,27-tetrol into 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid (PMID: 8496170).
5beta-Cholestane-3alpha,7alpha,24,26-tetrol
5beta-Cholestane-3alpha,7alpha,24,26-tetrol is also known as 5β-cholestan-3α,7α,24,27-tetrol. 5beta-Cholestane-3alpha,7alpha,24,26-tetrol is considered to be practically insoluble (in water) and relatively neutral. 5beta-Cholestane-3alpha,7alpha,24,26-tetrol is a bile acid lipid molecule
5a-Cholestane-3a,7a,12a,25-tetrol
5a-Cholestane-3a,7a,12a,25-tetrol is a bile alcohols which is excreted mainly as glucurono-conjugates in bile and urine, and as unconjugated form in feces of patients with cerebrotendinous xanthomatosis (PMID 3700361).
5beta-Cholestane-3alpha,7alpha,12alpha,25-tetrol
5β-Cholestane-3α,7α,12α,25-tetrol is an intermediate in the bile acid synthetic pathway, and is secreted into the bile and urine following glucuronidation. It does not undergo enterohepatic circulation. In cerebrotendinous xanthomatosis (CTX), a bile acid synthesis disorder caused by sterol 27-hydroxylase (CYP27) deficiency, early intermediates and cholestanol accumulate in a variety of tissues, and glucuronides of 25-hydroxylated bile alcohols are released in bile, blood, and urine (PMID: 11181760). Bile acid synthesis from cholesterol is tightly regulated via a feedback mechanism mediated by the farnesoid X receptor (FXR), a nuclear receptor activated by bile acids. Synthesis via the classic pathway is initiated by a series of cholesterol ring modifications and followed by the side chain cleavage. The enhanced cholesterol 7 alpha-hydroxylase (CYP7A1) expression in CYP27 deficiency may be the result of a decreased flux of bile acids and bile alcohols into the liver, while production of FXR-activating 5β-cholestane-3α,7α,12α,25-tetrol is increased (PMID: 15145977).
5b-Cholestane-3a,7a,12a,23-Tetrol
5b-Cholestane-3a,7a,12a,23-Tetrol is a bile present in the urine samples of patients with cerebrotendinous xanthomatosis (CTX). (PMID 6883710 ).
27-Deoxy-5alpha-cyprinol
27-Deoxy-5alpha-cyprinol is found in fishes. 27-Deoxy-5alpha-cyprinol is isolated from lungfish and car
(3beta,5alpha,12beta)-Cholestane-3,7,12,25-tetrol
(3beta, 5alpha, 6beta)-Cholestane-3, 5, 6, 9-tetrol
(3alpha, 5beta, 7alpha, 12alpha, 23R)-Cholestane-3, 7, 12, 23-tetrol
(20R,24S)-5alpha-cholestane-3beta,6beta,15alpha,24-tetraol
5alpha-Cholestan-3beta,5,6beta,19-tetraol|nephalsterol
5alpha-Cholestan-3beta,5,6beta,7beta-tetrol|5alpha-cholestane-3beta,5,6beta,7beta-tetrol|cholestane-3beta,5alpha,6beta,7beta-tetrol
(3beta,5alpha,6beta,11beta)-cholestane-3,5,6,11-tetrol|cholestane-3beta,5alpha,6beta,11beta-tetrol|menellsteroid A
(3alpha, 5beta, 7alpha)-Cholestane-3, 7, 25, 26-tetrol|(3alpha, 5beta, 7alpha)-Cholestane-3, 7, 26, 27-tetrol
(1beta, 3beta, 5alpha, 6beta)-Cholestane-1, 3, 5, 6-tetrol|(1beta,3beta,5alpha,6beta)-cholestane-1,3,5,6-tetraol|1beta,3beta,5alpha,6beta-tetrahydroxycholestane|5alpha-cholestane-1beta,3beta,5,6beta-tetrol|cholestan-1beta,3beta,5alpha,6beta-tetrol|cholestane-1beta,3beta,5alpha,6beta-tetraol|cholestane-1beta,3beta,5alpha,6beta-tetrol
(3alpha, 5beta, 7alpha, 12alpha, 24S)-Cholestane-3, 7, 12, 24-tetrol
(3R,5S,7R,9S,10S,12S,13R,14S,17R)-17-((2R)-7-hydroxy-6-methylheptan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
(3R,5R,7R,9S,10S,12S,13R,14S,17R)-17-((2R)-7-hydroxy-6-methylheptan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
5b-Cholestane-3a,7a,12a,25-tetrol
(25S)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol
(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol
5beta-Cholestane-3alpha,7alpha,12alpha,26-tetrol
(24S)-5beta-cholestane-3alpha,7alpha,12alpha,24-tetrol
5beta-Cholestane-3alpha,7alpha,12alpha,24-tetrol with S-configuration at C-24.
5a-Cholestane-3a,7a,12a,25-tetrol
PE(22:1(13Z)/22:2(13Z,16Z)) is a phosphatidylethanolamine (PE or GPEtn). It is a glycerophospholipid in which a phosphorylethanolamine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, glycerophosphoethanolamines can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. PE(22:1(13Z)/22:2(13Z,16Z)), in particular, consists of one chain of erucic acid at the C-1 position and one chain of docosadienoic acid at the C-2 position. The erucic acid moiety is derived from seed oils and avocados, while the docosadienoic acid moiety is derived from animal fats. Phospholipids, are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. 5a-Cholestane-3a,7a,12a,25-tetrol is a bile alcohols which is excreted mainly as glucurono-conjugates in bile and urine, and as unconjugated form in feces of patients with cerebrotendinous xanthomatosis (PMID 3700361).
(3R,5R,7R,8R,9S,10S,12S,13R,14S)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
(24S)-5beta-cholestane-3alpha,7alpha,24,26-tetrol
5beta-Cholestane-3alpha,7alpha,24,26-tetrol with S-configuration at C-24.
[1-hydroxy-3-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoxy]propan-2-yl] hexanoate
[1-[(10Z,13Z,16Z)-docosa-10,13,16-trienoxy]-3-hydroxypropan-2-yl] acetate
[1-hydroxy-3-[(11Z,14Z,17Z)-icosa-11,14,17-trienoxy]propan-2-yl] butanoate
(1-hydroxy-3-octoxypropan-2-yl) (7Z,10Z,13Z)-hexadeca-7,10,13-trienoate
[1-[(7Z,10Z,13Z)-hexadeca-7,10,13-trienoxy]-3-hydroxypropan-2-yl] octanoate
DG(24:3)
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