Chemical Formula: C27H27ClFN3OS

Chemical Formula C27H27ClFN3OS

Found 1 metabolite its formula value is C27H27ClFN3OS

R 59-022 (hydrochloride)

R 59-022 (hydrochloride)

C27H27ClFN3OS (495.15472940000006)


R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 μM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].