Chemical Formula: C26H24ClNO3

Chemical Formula C26H24ClNO3

Found 1 metabolite its formula value is C26H24ClNO3

G907

G907

C26H24ClNO3 (433.1445)


G907 is a selective antagonist of ATP-binding cassette (ABC) transporter MsbA with anti-microbial activity. G907 inhibits E. coli MsbA with an IC50 value of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket[1][2].