Chemical Formula: C25H25N3O2S
Chemical Formula C25H25N3O2S
Found 2 metabolite its formula value is C25H25N3O2S
NVP 231
NVP 231
NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK[1]. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage[2].