Chemical Formula: C23H25F3N4O3

Chemical Formula C23H25F3N4O3

Found 1 metabolite its formula value is C23H25F3N4O3

BI-3406

BI-3406

C23H25F3N4O3 (462.1878656)


BI-3406 (compound I-6) is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity[1][2].