Chemical Formula: C22H31ClF3N3O4S3

Chemical Formula C22H31ClF3N3O4S3

Found 1 metabolite its formula value is C22H31ClF3N3O4S3

6H05 (TFA)

6H05 TFA is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value: Target: K-Ras G12C 6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].