Chemical Formula: C22H27FN3NaO6S
Chemical Formula C22H27FN3NaO6S
Found 1 metabolite its formula value is C22H27FN3NaO6S
Rosuvastatin calcium
Rosuvastatin calcium
C22H27FN3NaO6S (503.1502214000001)
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].