Chemical Formula: C22H24ClN3OS2

Chemical Formula C22H24ClN3OS2

Found 1 metabolite its formula value is C22H24ClN3OS2

spiclomazine

spiclomazine

C22H24ClN3OS2 (445.1049244)


C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent Spiclomazine (Clospirazine) is a potent mutant KRAS(G12C) inhibitor that selectively inhibits mutant KRAS-driven pancreatic cancer. Spiclomazine can eliminate KRas-GTP levels in KRAS-driven pancreatic cancer and effectively inhibit RAS-mediated signaling. Spiclomazine significantly inhibits tumor progression in mouse renal capsule xenotransplantation models[1].