Chemical Formula: C22H22Cl2F3NO

Chemical Formula C22H22Cl2F3NO

Found 2 metabolite its formula value is C22H22Cl2F3NO

N-debutylhalofantrine

3-(butylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol

C22H22Cl2F3NO (443.1030458)


N-debutylhalofantrine is a metabolite of halofantrine. Halofantrine is a drug used to treat malaria. Halofantrines structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown. A crystallographic study have shown that halofantrine binds to hematin in vitro, suggesting a possible mechanism of action. (Wikipedia) D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents

   

Desmethylhalofantrine

1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol

C22H22Cl2F3NO (443.1030458)