Chemical Formula: C22H20N4OS2
Chemical Formula C22H20N4OS2
Found 1 metabolite its formula value is C22H20N4OS2
SirReal2
SirReal2
SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140?nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1[1].