Chemical Formula: C22H15ClN2O2

Chemical Formula C22H15ClN2O2

Found 1 metabolite its formula value is C22H15ClN2O2

BMS-984923

BMS-984923

C22H15ClN2O2 (374.0822)


BMS-984923, a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling[1][2].