Chemical Formula: C21H23Cl3N4O2

Chemical Formula C21H23Cl3N4O2

Found 1 metabolite its formula value is C21H23Cl3N4O2

Ulixertinib (hydrochloride)

Ulixertinib (hydrochloride)

C21H23Cl3N4O2 (468.0886508)


Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2].