Chemical Formula: C21H22BrFN4O2

Chemical Formula C21H22BrFN4O2

Found 1 metabolite its formula value is C21H22BrFN4O2

N-Desmethyl vandetanib

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine

C21H22BrFN4O2 (460.091)


N-Desmethyl vandetanib is a metabolite of vandetanib. Vandetanib (rINN, trade name Caprelsa), also known as ZD6474, is an antagonist of the vascular endothelial growth factor receptor (VEGFR) and the epidermal growth factor receptor (EGFR). It is a tyrosine kinase inhibitor, being developed by AstraZeneca. It has a third target: inhibiting RET-tyrosine kinase activity, an important growth driver in certain types of thyroid cancer (Wikipedia)