Chemical Formula: C21H19ClF3N5O2S

Chemical Formula C21H19ClF3N5O2S

Found 1 metabolite its formula value is C21H19ClF3N5O2S

Lu AF27139

C21H19ClF3N5O2S (497.0900020000001)

Lu AF27139 is a potent, selective, and orally active antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 has rodent-active and CNS-penetrant character. Lu AF27139 has the potential for the research of CNS diseases[1].