Chemical Formula: C20H41NO2

Chemical Formula C20H41NO2

Found 26 metabolite its formula value is C20H41NO2

N,N-Dimethylsphingosine

(S-(R,S-(e)))-2-(dimethylamino)-4-Octadecene-1,3-diol

C20H41NO2 (327.31371260000003)


N,N-Dimethylsphingosine is an inhibitor of sphingosine kinase. It is a natural metabolite of sphingosine in some cancer cell lines and tissues. N,N-Dimethylsphingosine inhibited U937 cell sphingosine kinase with a Ki value of 3.1 µM. N,N-Dimethylsphingosine induces apoptosis, but it is not an inhibitor of protein kinase C. N,N-Dimethylsphingosine (DMS) has recently been identified as an inducer of pain in a rat model of chronic pain. (PMID: 22267119) It has properties similar to capsaicin (PMID: 16740613). Other studies have indicated that DMS inhibits airway inflammation in asthma (PMID: 18359884) and is cardioprotective (PMID: 16831409). N,N-Dimethylsphingosine is an inhibitor of sphingosine kinase. It is a natural metabolite of sphingosine in some cancer cell lines and tissues.1 N,N-Dimethylsphingosine inhibited U937 cell sphingosine kinase with a Ki value of 3.1 ?M.2 N,N-Dimethylsphingosine induces apoptosis, but it is not an inhibitor of protein kinase C. [HMDB] D004791 - Enzyme Inhibitors

   

Stearoylethanolamide

Monoethanolamine stearic acid amide

C20H41NO2 (327.31371260000003)


Stearoylethanolamide is a N-acylethanolamine. N-acylethanolamines (NAEs) constitute a class of lipid compounds naturally present in both animal and plant membranes as constituents of the membrane-bound phospholipid, N-acylphosphatidylethanolamine (NAPE). NAPE is composed of a third fatty acid moiety linked to the amino head group of the commonly occurring membrane phospholipid, phosphatidylethanolamine. NAEs are released from NAPE by phospholipase D-type hydrolases in response to a variety of stimuli. Transient NAE release and accumulation has been attributed a variety of biological activities, including neurotransmission, membrane protection, and immunomodulation in animals. N-oleoylethanolamine is an inhibitor of the sphingolipid signaling pathway, via specific ceramidase inhibition (ceramidase converts ceramide to sphingosine). N-oleoylethanolamine blocks the effects of TNF- and arachidonic acid on intracellular Ca concentration. (PMID: 12692337, 12056855, 12560208, 11997249) [HMDB] Stearoylethanolamide is an N-acylethanolamine. N-acylethanolamines (NAEs) constitute a class of lipid compounds naturally present in both animal and plant membranes as constituents of the membrane-bound phospholipid, N-acylphosphatidylethanolamine (NAPE). NAPE is composed of a third fatty acid moiety linked to the amino head group of the commonly occurring membrane phospholipid, phosphatidylethanolamine. NAEs are released from NAPE by phospholipase D-type hydrolases in response to a variety of stimuli. Transient NAE release and accumulation has been attributed a variety of biological activities, including neurotransmission, membrane protection, and immunomodulation in animals. N-oleoylethanolamine is an inhibitor of the sphingolipid signaling pathway, via specific ceramidase inhibition (ceramidase converts ceramide to sphingosine). N-oleoylethanolamine blocks the effects of TNF- and arachidonic acid on intracellular Ca concentration. (PMID: 12692337, 12056855, 12560208, 11997249). Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.

   

gamma-Aminobutyric acid cetyl ester

gamma-Aminobutyric acid cetyl ester hydrochloride

C20H41NO2 (327.31371260000003)


   

2-(Dimethylamino)octadec-4-ene-1,3-diol

2-(dimethylamino)octadec-4-ene-1,3-diol

C20H41NO2 (327.31371260000003)


   

3-Amino-2-methoxynonadec-5-en-4-ol

3-Amino-2-methoxynonadec-5-en-4-ol

C20H41NO2 (327.31371260000003)


   

N-(1-Hydroxyethyl)octadecanamide

N-(1-Hydroxyethyl)octadecanimidate

C20H41NO2 (327.31371260000003)


   

sphinganine (C20)

(1,3-dihydroxyicosan-2-yl)azaniumyl

C20H41NO2 (327.31371260000003)


Sphinganine (c20) is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Sphinganine (c20) can be found in a number of food items such as durian, black mulberry, pepper (c. frutescens), and pineapple, which makes sphinganine (c20) a potential biomarker for the consumption of these food products.

   

6-(13-hydroxytetradecyl)-2-methyl-3-piperidinol

6-(13-hydroxytetradecyl)-2-methyl-3-piperidinol

C20H41NO2 (327.31371260000003)


   

2-amino-1,3-dihydroxy-eicos-4-ene

2-amino-1,3-dihydroxy-eicos-4-ene

C20H41NO2 (327.31371260000003)


   
   

Stearoyl-EA

N-(2-hydroxyethyl)octadecanamide

C20H41NO2 (327.31371260000003)


Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.

   

D-erythro-Sphingosine C-20

2S-amino-4E-eicosene-1,3R-diol

C20H41NO2 (327.31371260000003)


   

NAE 18:0

N-(Octadecanoyl)-ethanolamine

C20H41NO2 (327.31371260000003)


   

C20 sphingosine

(2S,3R,4E)-2-aminoeicos-4-ene-1,3-diol

C20H41NO2 (327.31371260000003)


A sphingoid that is the C20 analogue of sphingosine.

   

SPB 20:1;O2

N,N-dimethylsphing-4-enine

C20H41NO2 (327.31371260000003)


D004791 - Enzyme Inhibitors

   

(Z)-octadec-9-enylammonium acetate

(Z)-octadec-9-enylammonium acetate

C20H41NO2 (327.31371260000003)


   
   

2-(Dimethylamino)-4-octadecene-1,3-diol

2-(Dimethylamino)-4-octadecene-1,3-diol

C20H41NO2 (327.31371260000003)


   

3-Amino-2-methoxynonadec-5-en-4-ol

3-Amino-2-methoxynonadec-5-en-4-ol

C20H41NO2 (327.31371260000003)


   
   

Stearoylethanolamide

N-(2-hydroxyethyl)octadecanamide

C20H41NO2 (327.31371260000003)


Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.

   

N,N-Dimethylsphingosine

N,N-Dimethylsphingosine

C20H41NO2 (327.31371260000003)


A sphingoid that is sphingosine in which the two amino hydrogens are replaced by methyl groups. D004791 - Enzyme Inhibitors

   

AEA(18:0)

AEA(18:0)

C20H41NO2 (327.31371260000003)


Provides by LipidSearch Vendor. © Copyright 2006-2024 Thermo Fisher Scientific Inc. All rights reserved

   

Sphingosine (d20:1)

SPH(d20:1)

C20H41NO2 (327.31371260000003)


Provides by LipidSearch Vendor. © Copyright 2006-2024 Thermo Fisher Scientific Inc. All rights reserved