3-Amino-2-methoxynonadec-5-en-4-ol (BioDeep_00000183379)
human metabolite blood metabolite
代谢物信息卡片
3-Amino-2-methoxynonadec-5-en-4-ol
化学式: C20H41NO2 (327.31371260000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCC=CC(O)C(N)C(C)OC
InChI: InChI=1S/C20H41NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(22)20(21)18(2)23-3/h16-20,22H,4-15,21H2,1-3H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Goutam Chakraborty, Mitsuo Saito, Relish Shah, Rui-Fen Mao, Csaba Vadasz, Mariko Saito. Ethanol triggers sphingosine 1-phosphate elevation along with neuroapoptosis in the developing mouse brain.
Journal of neurochemistry.
2012 Jun; 121(5):806-17. doi:
10.1111/j.1471-4159.2012.07723.x. [PMID: 22393932] - Léon J A Spijkers, Rob F P van den Akker, Ben J A Janssen, Jacques J Debets, Jo G R De Mey, Erik S G Stroes, Bert-Jan H van den Born, Dayanjan S Wijesinghe, Charles E Chalfant, Luke MacAleese, Gert B Eijkel, Ron M A Heeren, Astrid E Alewijnse, Stephan L M Peters. Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide.
PloS one.
2011; 6(7):e21817. doi:
10.1371/journal.pone.0021817. [PMID: 21818267] - Kiran S Panickar, Richard A Anderson. Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia.
International journal of molecular sciences.
2011; 12(11):8181-207. doi:
10.3390/ijms12118181. [PMID: 22174658] - Mihwa Kim, Minjae Kim, Sang Won Park, Stuart M Pitson, H Thomas Lee. Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generation.
American journal of nephrology.
2010; 31(4):353-62. doi:
10.1159/000298339. [PMID: 20234131] - Bradley K Wacker, Tae Sung Park, Jeffrey M Gidday. Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2.
Stroke.
2009 Oct; 40(10):3342-8. doi:
10.1161/strokeaha.109.560714. [PMID: 19644058] - Antonina Kolmakova, Mohanraj Rajesh, David Zang, Roberto Pili, Subroto Chatterjee. VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo.
Glycoconjugate journal.
2009 Jul; 26(5):547-58. doi:
10.1007/s10719-008-9206-9. [PMID: 19219548] - Sarah T Pruett, Anatoliy Bushnev, Kerri Hagedorn, Madhura Adiga, Christopher A Haynes, M Cameron Sullards, Dennis C Liotta, Alfred H Merrill. Biodiversity of sphingoid bases ('sphingosines') and related amino alcohols.
Journal of lipid research.
2008 Aug; 49(8):1621-39. doi:
10.1194/jlr.r800012-jlr200. [PMID: 18499644] - Salvador Borges, Sarah Lindstrom, Cameron Walters, Ajithkumar Warrier, Martin Wilson. Discrete influx events refill depleted Ca2+ stores in a chick retinal neuron.
The Journal of physiology.
2008 Jan; 586(2):605-26. doi:
10.1113/jphysiol.2007.143339. [PMID: 18033816] - Marie-Noëlle Raymond, Christine Bole-Feysot, Yoshiko Banno, Zahra Tanfin, Philippe Robin. Endothelin-1 inhibits apoptosis through a sphingosine kinase 1-dependent mechanism in uterine leiomyoma ELT3 cells.
Endocrinology.
2006 Dec; 147(12):5873-82. doi:
10.1210/en.2006-0291. [PMID: 16959847] - Hesham M El-Shewy, Korey R Johnson, Mi-Hye Lee, Ayad A Jaffa, Lina M Obeid, Louis M Luttrell. Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors.
The Journal of biological chemistry.
2006 Oct; 281(42):31399-407. doi:
10.1074/jbc.m605339200. [PMID: 16926156] - Yuefang Ma, Stuart Pitson, Timothy Hercus, Jane Murphy, Angel Lopez, Joanna Woodcock. Sphingosine activates protein kinase A type II by a novel cAMP-independent mechanism.
The Journal of biological chemistry.
2005 Jul; 280(28):26011-7. doi:
10.1074/jbc.m409081200. [PMID: 15883165] - Kiyoshi Itagaki, Kolenkode B Kannan, Carl J Hauser. Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils.
Journal of leukocyte biology.
2005 Feb; 77(2):181-9. doi:
10.1189/jlb.0704390. [PMID: 15522918] - Jih-Pyang Wang, Mei-Feng Hsu, Horng-Huey Ko, Chun-Nan Lin. Stimulation of cellular free Ca2+ elevation and inhibition of store-operated Ca2+ entry by kazinol B in neutrophils.
Naunyn-Schmiedeberg's archives of pharmacology.
2004 Dec; 370(6):500-9. doi:
10.1007/s00210-004-0997-3. [PMID: 15558242] - Toshitada Fujita, Taro Okada, Shun Hayashi, Saleem Jahangeer, Noriko Miwa, Shun-ichi Nakamura. Delta-catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1.
The Biochemical journal.
2004 Sep; 382(Pt 2):717-23. doi:
10.1042/bj20040141. [PMID: 15193146] - Norio Hanafusa, Yutaka Yatomi, Koei Yamada, Yuichi Hori, Masaomi Nangaku, Toshihiro Okuda, Toshiro Fujita, Kiyoshi Kurokawa, Masafumi Fukagawa. Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2002 Apr; 17(4):580-6. doi:
10.1093/ndt/17.4.580. [PMID: 11917049] - O Cuvillier, T Levade. Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria.
Blood.
2001 Nov; 98(9):2828-36. doi:
10.1182/blood.v98.9.2828. [PMID: 11675357] - J S Karliner, N Honbo, K Summers, M O Gray, E J Goetzl. The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes.
Journal of molecular and cellular cardiology.
2001 Sep; 33(9):1713-7. doi:
10.1006/jmcc.2001.1429. [PMID: 11549349] - V Aas, S Algerøy, K L Sand, J G Iversen. Fibronectin promotes calcium signaling by interferon-gamma in human neutrophils via G-protein and sphingosine kinase-dependent mechanisms.
Cell communication & adhesion.
2001; 8(3):125-38. doi:
10.3109/15419060109080712. [PMID: 11936187] - . .
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