Chemical Formula: C20H18ClF6N3O2
Chemical Formula C20H18ClF6N3O2
Found 1 metabolite its formula value is C20H18ClF6N3O2
UC2288
UC2288
C20H18ClF6N3O2 (481.09916699999997)
UC2288 is a novel, cell-permeable, and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 decreases p21 mRNA expression independently of p53, and attenuates p21 protein levels with minimal effect on p21 protein stability. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM[1].