Chemical Formula: C20H17F2N3O2

Chemical Formula C20H17F2N3O2

Found 2 metabolite its formula value is C20H17F2N3O2

ADX-47273

ADX-47273

C20H17F2N3O2 (369.1289)


ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities[1][2].

   

(R)-ADX-47273

(R)-ADX-47273

C20H17F2N3O2 (369.1289)


(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .