Chemical Formula: C18H20N4

Chemical Formula C18H20N4

Found 4 metabolite its formula value is C18H20N4

Lerisetron

1-benzyl-2-(piperazin-1-yl)-1H-1,3-benzodiazole

C18H20N4 (292.168788)


C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist > C94726 - 5-HT3 Receptor Antagonist C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent Lerisetron is a potent 5-HT3 antagonists and possess high-affinity binding for the 5-HT3 receptors with pKi value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats[1].

   

6-Ethyl-5-methyl-3-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-2-py razinecarbonitrile

6-Ethyl-5-methyl-3-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-2-py razinecarbonitrile

C18H20N4 (292.168788)


   

N-(3-phenyl-2-propen-1-ylidene)-4-(2-pyridinyl)-1-piperazinamine

N-(3-phenyl-2-propen-1-ylidene)-4-(2-pyridinyl)-1-piperazinamine

C18H20N4 (292.168788)


   

Deschloroclozapine

Deschloroclozapine

C18H20N4 (292.168788)


Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3].