Chemical Formula: C18H14ClNO4
Chemical Formula C18H14ClNO4
Found 3 metabolite its formula value is C18H14ClNO4
O-Desmethylindomethacin
2-[1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-1H-indol-3-yl]acetic acid
O-Desmethylindomethacin is a metaboite of Indomethacin. Indomethacin is metabolized in humans by O-demethylation, and by acyl glucuronidation to the 1-O-glucuronide. Indomethacin and O-desmethylindomethacin may be glucuronidated in the kidney. Probenecid is a known substrate for renal glucuronidation. If indomethacin is glucuronidated in the human kidney like probenecid, then this glucuronidation might be reduced or inhibited under probenecid co-medication. (PMID: 8156046)
1-(4-chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acid
1-(4-chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acid
