Chemical Formula: C18H13Cl2N3O3S

Chemical Formula C18H13Cl2N3O3S

Found 2 metabolite its formula value is C18H13Cl2N3O3S

6-chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide

6-chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide

C18H13Cl2N3O3S (421.0054648)


   

VU 0364439

VU 0364439

C18H13Cl2N3O3S (421.0054648)


VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM. IC50 Value: 19.8 nM(EC50) Target: mGluR in vitro: in vivo: VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63\% remaining) than RLM (2\% remaining).