Chemical Formula: C17H10F5NO4S
Chemical Formula C17H10F5NO4S
Found 2 metabolite its formula value is C17H10F5NO4S
(Rac)-PT2399
(Rac)-PT2399
C17H10F5NO4S (419.0250680000001)
(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM[1].
PT2399
PT2399
C17H10F5NO4S (419.0250680000001)
PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo[1][2][3].