Chemical Formula: C16H26N2O15P2

Chemical Formula C16H26N2O15P2

Found 18 metabolite its formula value is C16H26N2O15P2

Deoxythymidine diphosphate-L-rhamnose

[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl (2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name)

C16H26N2O15P2 (548.0808386)


Deoxythymidine diphosphate-L-rhamnose (dTDP-L-rhamnose) is the precursor of L-rhamnose, a saccharide required for the virulence of some pathogenic bacteria. In gram-negative bacteria such as Salmonella enterica, Vibrio cholerae, or Escherichia coli 075:K5, L-rhamnose is an important residue in the O-antigen of lipopolysaccharides, which are essential for resistance to serum killing and colonization. In gram-positive bacteria such as streptococci, the capsule is a recognized virulence factor. For example, L-rhamnose is known to be present in the capsule of Streptococcus suis, a causative agent of meningitis in humans. In Streptococcus mutans, L-rhamnose containing polysaccharides have been implicated in tooth surface colonization and adherence to kidney, muscle, and heart tissues. In mycobacteria, L-rhamnose is fundamental to the structural integrity of the cell wall since it connects the inner peptidoglycan layer to the arabinogalactan polysaccharides. dTDP-L-rhamnose is synthesized from glucose-1-phosphate and deoxythymidine triphosphate (dTTP) via a pathway involving four distinct enzymes. Whereas common sugars such as glucose, fructose, and mannose are all D-configured, bacteria commonly utilize the L-configured carbohydrates in pharmacologically active compounds and their cell-wall structures. The bacterial cell wall is unique to bacteria; neither the cell wall nor the enzymes and chemical intermediates in its formation have analogues in humans. The enzymes involved in dTDP-L-rhamnose synthesis are potential targets for the design of new therapeutic agents (PMID: 10802738, 12773151). 2-deoxy-thymidine-beta-l-rhamnose, also known as dtdp-6-deoxy-L-mannose or thymidine diphosphate-L-rhamnose, is a member of the class of compounds known as pyrimidine nucleotide sugars. Pyrimidine nucleotide sugars are pyrimidine nucleotides bound to a saccharide derivative through the terminal phosphate group. 2-deoxy-thymidine-beta-l-rhamnose is soluble (in water) and a moderately acidic compound (based on its pKa). 2-deoxy-thymidine-beta-l-rhamnose can be found in a number of food items such as black salsify, dill, roman camomile, and tea leaf willow, which makes 2-deoxy-thymidine-beta-l-rhamnose a potential biomarker for the consumption of these food products. DTDP-beta-L-rhamnose is the beta-anomer of dTDP-L-rhamnose. It has a role as an Escherichia coli metabolite. It is functionally related to a dTDP-L-mannose. It is a conjugate acid of a dTDP-6-deoxy-beta-L-mannose(2-). Deoxythymidine diphosphate-L-rhamnose is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). The beta-anomer of dTDP-L-rhamnose.

   

dTDP-L-dihydrostreptose

[(2R,3R,4S,5S)-3,4-dihydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl] [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate

C16H26N2O15P2 (548.0808386)


   
   
   

dTDP-6-deoxy-D-allose

dTDP-6-deoxy-alpha-D-allose

C16H26N2O15P2 (548.0808386)


   

[(2r,3s,5r)-3-Hydroxy-5-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)tetrahydrofuran-2-Yl]methyl (2r,3r,4s,5s,6r)-3,4,5-Trihydroxy-6-Methyltetrahydro-2h-Pyran-2-Yl Dihydrogen Diphosphate

[(2r,3s,5r)-3-Hydroxy-5-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)tetrahydrofuran-2-Yl]methyl (2r,3r,4s,5s,6r)-3,4,5-Trihydroxy-6-Methyltetrahydro-2h-Pyran-2-Yl Dihydrogen Diphosphate

C16H26N2O15P2 (548.0808386)


   

dTDP-6-deoxy-alpha-D-allose

dTDP-6-deoxy-alpha-D-allose

C16H26N2O15P2 (548.0808386)


   

[(2S,3R,4R,5S)-3,4-dihydroxy-5-(1-hydroxyethyl)oxolan-2-yl] [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate

[(2S,3R,4R,5S)-3,4-dihydroxy-5-(1-hydroxyethyl)oxolan-2-yl] [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate

C16H26N2O15P2 (548.0808386)


   

Deoxythymidine diphosphate-l-rhamnose

Deoxythymidine diphosphate-l-rhamnose

C16H26N2O15P2 (548.0808386)


   
   
   
   

dTDP-beta-D-fucofuranose

dTDP-beta-D-fucofuranose

C16H26N2O15P2 (548.0808386)


A dTDP-sugar having beta-D-fucofuranose as the sugar component.

   

thymidine 5-[3-(6-deoxy-D-galactopyranosyl) dihydrogen diphosphate]

thymidine 5-[3-(6-deoxy-D-galactopyranosyl) dihydrogen diphosphate]

C16H26N2O15P2 (548.0808386)


   
   
   

dTDP-alpha-L-rhamnose

dTDP-alpha-L-rhamnose

C16H26N2O15P2 (548.0808386)


The alpha-anomer of dTDP-L-rhamnose.