Chemical Formula: C16H17N

Chemical Formula C16H17N

Found 23 metabolite its formula value is C16H17N

1-Benzyl-1,2,3,4-tetrahydroisoquinoline

1,2,3,4-tetrahydro-1-(Phenylmethyl)isoquinoline hydrochloride

C16H17N (223.1360922)


1-benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ) as a possible PD-eliciting neurotoxin and evaluated its characteristics relevant to Parkinson disease (PD). 1BnTIQ exist in mammals and is proposed as possible PD-eliciting neurotoxin. PD is believed to be induced by the interaction of genetic predisposition and environmental factors, and a type of neurotoxin is proposed to be one of the environmental factors. 1BnTIQ inhibits [3H] dopamine uptake in HEK293 cells which stably express dopamine transporter. 1BnTIQ also inhibits NADH-ubiquinone oxidoreductase (complex I) in the mitochondrial respiratory chain. 1BnTIQ decreases the dopamine content in the mesencephalon in both dose- and time-dependent manners and it irreversibly reduced the dopamine content. Furthermore, it causes morphological changes in tyrosine hydroxylase-positive cells in the mesencephalon and reduced the number of cells. (PMID 12440154) [HMDB] 1-benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ) as a possible PD-eliciting neurotoxin and evaluated its characteristics relevant to Parkinson disease (PD). 1BnTIQ exist in mammals and is proposed as possible PD-eliciting neurotoxin. PD is believed to be induced by the interaction of genetic predisposition and environmental factors, and a type of neurotoxin is proposed to be one of the environmental factors. 1BnTIQ inhibits [3H] dopamine uptake in HEK293 cells which stably express dopamine transporter. 1BnTIQ also inhibits NADH-ubiquinone oxidoreductase (complex I) in the mitochondrial respiratory chain. 1BnTIQ decreases the dopamine content in the mesencephalon in both dose- and time-dependent manners and it irreversibly reduced the dopamine content. Furthermore, it causes morphological changes in tyrosine hydroxylase-positive cells in the mesencephalon and reduced the number of cells. (PMID 12440154). D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists

   

3,3-Diphenylpyrrolidine

3,3-Diphenylpyrrolidine

C16H17N (223.1360922)


   

4-Dimethylaminostilbene

N,N-dimethyl-4-(2-phenylethenyl)aniline

C16H17N (223.1360922)


   

(2S,5S)-2,5-Diphenylpyrrolidine

(2S,5S)-2,5-Diphenylpyrrolidine

C16H17N (223.1360922)


   

2-tert-butyl-9H-carbazole

2-tert-butyl-9H-carbazole

C16H17N (223.1360922)


   

4-Dimethylaminostilbene

N,N-Dimethyl-p-styrylaniline

C16H17N (223.1360922)


   

1H-Benz[f]isoindole,2-cyclopropyl-2,3-dihydro-6-methyl-(9CI)

1H-Benz[f]isoindole,2-cyclopropyl-2,3-dihydro-6-methyl-(9CI)

C16H17N (223.1360922)


   

9-ethyl-3,6-dimethylcarbazole

9-ethyl-3,6-dimethylcarbazole

C16H17N (223.1360922)


   

9H-Carbazole, 9-butyl-

9H-Carbazole, 9-butyl-

C16H17N (223.1360922)


   

5-aminomethyl-dibenzosuberane

5-aminomethyl-dibenzosuberane

C16H17N (223.1360922)


   

(2R,5R)-2,5-Diphenylpyrrolidine

(2R,5R)-2,5-Diphenylpyrrolidine

C16H17N (223.1360922)


   

N-PHENYL-1,2,3,4-TETRAHYDRO-2-AMINONAPHTHALENE

N-PHENYL-1,2,3,4-TETRAHYDRO-2-AMINONAPHTHALENE

C16H17N (223.1360922)


   

N-benzyl-2,3-dihydro-1H-inden-1-amine

N-benzyl-2,3-dihydro-1H-inden-1-amine

C16H17N (223.1360922)


   

(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-yl)methanamine

(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-yl)methanamine

C16H17N (223.1360922)


   

1-benzhydrylazetane

1-benzhydrylazetane

C16H17N (223.1360922)


   

2-[1,1-BIPHENYL]-2-YL-PYRROLIDINE

2-[1,1-BIPHENYL]-2-YL-PYRROLIDINE

C16H17N (223.1360922)


   

(S)-2-(2-PHENYLPHENYL)PYRROLIDINE

(S)-2-(2-PHENYLPHENYL)PYRROLIDINE

C16H17N (223.1360922)


   

(S)-2-(4-PHENYLPHENYL)PYRROLIDINE

(S)-2-(4-PHENYLPHENYL)PYRROLIDINE

C16H17N (223.1360922)


   

4,5-diethylpyrrolo[1,2-a]quinoline

4,5-diethylpyrrolo[1,2-a]quinoline

C16H17N (223.1360922)


   

2-(4-Biphenylyl)pyrrolidine

2-(4-Biphenylyl)pyrrolidine

C16H17N (223.1360922)


   

1H-Indole,1-(2,5-dimethylphenyl)-2,3-dihydro-(9CI)

1H-Indole,1-(2,5-dimethylphenyl)-2,3-dihydro-(9CI)

C16H17N (223.1360922)


   

1-Benzyl-1,2,3,4-tetrahydroisoquinoline

Isoquinoline,1,2,3,4-tetrahydro-1-(phenylmethyl)-

C16H17N (223.1360922)


D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists

   

Benzyltetrahydroisoquinoline

Benzyltetrahydroisoquinoline

C16H17N (223.1360922)