Chemical Formula: C16H16IN3O3S

Chemical Formula C16H16IN3O3S

Found 1 metabolite its formula value is C16H16IN3O3S

MB710

MB710

C16H16IN3O3S (456.99570960000005)


MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a Kd of 4.1?μM. MB710 shows anticancer activity in p53-Y220C cell lines[1].