Chemical Formula: C16H12BrN3O4

Chemical Formula C16H12BrN3O4

Found 1 metabolite its formula value is C16H12BrN3O4

ASM-IN-1

ASM-IN-1

C16H12BrN3O4 (389.0011)


ASM-IN-1 is a potent and orally active acid sphingomyelinase (ASM) inhibitor with an IC50 value of 1.5 μM. ASM-IN-1 reduces lipid plaques in the aortic arch and aorta and reduces plasma ceramide concentration and Ox-LDL levels. ASM-IN-1 shows antiatherosclerotic and anti-inflammatory activity[1].