Chemical Formula: C16H11N3O2
Chemical Formula C16H11N3O2
Found 13 metabolite its formula value is C16H11N3O2
3-[(2Z,3E)-3-(Hydroxyimino)-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indol-2-one
3-nitroso-2',3'-dihydro-1H,1'H-[2,3'-biindole]-2'-one
Indirubin-3'-monoxime
3-nitroso-1H,1H-[2,3-biindole]-2-ol
Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 μM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
INDIRUBIN-3-MONOXIME
3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
A member of the class of biindoles that is indirubin in which the keto group at position 3 has undergone condensation with hydroxylamine to form the corresponding oxime. Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 μM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
1,2-Ethanedione, 1-(6-Methyl-2-pyridinyl)-2-(6-quinoxalinyl)-
1,2-Ethanedione, 1-(6-Methyl-2-pyridinyl)-2-(6-quinoxalinyl)-
2-AMINO-4-(5-METHYLFURAN-2-YL)-5H-INDENO[1,2-D]PYRIMIDIN-5-ONE
2-AMINO-4-(5-METHYLFURAN-2-YL)-5H-INDENO[1,2-D]PYRIMIDIN-5-ONE
N-[4-cyano-2-(1-naphthalenyl)-5-oxazolyl]acetamide
N-[4-cyano-2-(1-naphthalenyl)-5-oxazolyl]acetamide
9-hydroxy-8,11,19-triazatetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadeca-1(19),2,4,6,8,13,15,17-octaen-12-one
9-hydroxy-8,11,19-triazatetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadeca-1(19),2,4,6,8,13,15,17-octaen-12-one
8-hydroxy-1,9,12-triazatetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadeca-2,4,6,8,11,13,15,17-octaen-19-one
8-hydroxy-1,9,12-triazatetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadeca-2,4,6,8,11,13,15,17-octaen-19-one
