Chemical Formula: C14H13ClN2O2
Chemical Formula C14H13ClN2O2
Found 10 metabolite its formula value is C14H13ClN2O2
4-CHLORO-7-ISOPROPOXY-6-METHOXYQUINOLINE-3-CARBONITRILE
4-CHLORO-7-ISOPROPOXY-6-METHOXYQUINOLINE-3-CARBONITRILE
Benzoic acid,4-chloro-, 1-(4-methoxyphenyl)hydrazide
Benzoic acid,4-chloro-, 1-(4-methoxyphenyl)hydrazide
ethyl-2-methyl-4-(2-chlorophenyl)-5-pyrimidine carboxylate
ethyl-2-methyl-4-(2-chlorophenyl)-5-pyrimidine carboxylate
Ethyl 2-(4-chlorophenyl)-4-methyl-5-pyrimidinecarboxylate
Ethyl 2-(4-chlorophenyl)-4-methyl-5-pyrimidinecarboxylate
N-[4-chloro-2-[oxo(1H-pyrrol-2-yl)methyl]phenyl]propanamide
N-[4-chloro-2-[oxo(1H-pyrrol-2-yl)methyl]phenyl]propanamide
PT-262
PT-262
PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 μM. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity[1][2].