Chemical Formula: C14H11FN2O4

Chemical Formula C14H11FN2O4

Found 2 metabolite its formula value is C14H11FN2O4

   

AKB-6899

AKB-6899

C14H11FN2O4 (290.07028180000003)


AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2α stabilizer. AKB-6899 also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects[1].