Chemical Formula: C13H15ClN4
Chemical Formula C13H15ClN4
Found 3 metabolite its formula value is C13H15ClN4
VUF 10166
VUF 10166
VUF10166 is a potent and high-affinity 5-HT3 receptor antagonist, with Ki values of 0.04 nM (5-HT3A) and 22 nM (5-HT3AB). VUF10166 inhibits 5-HT-induced responses at 5-HT3A and 5-HT3AB receptors at nanomolar concentrations. At 5-HT3 receptor, VUF10166 at higher concentrations also acts as a partial agonist, with an EC50 of 5.2 μM[1].
4-[(4-chlorophenyl)methyl]-3-[(2R)-pyrrolidin-2-yl]-1,2,4-triazole
4-[(4-chlorophenyl)methyl]-3-[(2R)-pyrrolidin-2-yl]-1,2,4-triazole
