Chemical Formula: C12H13N3O4S

Chemical Formula C12H13N3O4S

Found 8 metabolite its formula value is C12H13N3O4S

N4-Acetylsulfamethoxazole

N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}ethanimidic acid

N4-Acetylsulfamethoxazole is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation catalyzed by liver extramitochondrial N-acetyl transferases. Acetylsulfamethoxazole is excreted in urine. Acetylsulfamethoxazole and sulfamethoxazole can be used as a probe for the molecular percentage enrichment of liver extramitochondrial acetyl-CoA. N4-Acetylsulfamethoxazole can be used as a reference for measuring sulfamethoxazole impurities and waste determination (PMID: 15307787). It is one of the critical aspects of urine and stone analysis (PMID: 3811034) and its quantitative determination in body fluids could be performed by reversed-phase high-performance liquid chromatography, a rapid, precise and simple procedure (PMID: 6668314). It is also reported the renal excretion rate of the metabolite N4-acetylsulfamethoxazole is not dependent on the urinary pH (PMID: 670346). N4-Acetylsulfamethoxazole is only found in individuals who have consumed the drug sulfamethoxazole. D000890 - Anti-Infective Agents > D013424 - Sulfanilamides CONFIDENCE standard compound; EAWAG_UCHEM_ID 299

N(1)-Acetylsulfamethoxazole

N-(4-aminobenzenesulfonyl)-N-(5-methyl-1,2-oxazol-3-yl)acetamide

C12H13N3O4S (295.0627)

D000890 - Anti-Infective Agents > D013424 - Sulfanilamides

8-(2-aminoethyl)-1,1-dioxo-2,3,4,6-tetrahydropyrrolo[2,3-g][1,4]benzothiazine-5,9-dione

C12H13N3O4S (295.0627)

Acetylsulfamethoxazole

N4-Acetyl-Sulfamethoxazole

C12H13N3O4S (295.0627)

D000890 - Anti-Infective Agents > D013424 - Sulfanilamides CONFIDENCE standard compound; INTERNAL_ID 2672 CONFIDENCE standard compound; INTERNAL_ID 8589 CONFIDENCE standard compound; INTERNAL_ID 4117 CONFIDENCE standard compound; INTERNAL_ID 2014

Chemical Formula: C12H13N3O4S