Chemical Formula: C11H12ClN3O2S
Chemical Formula C11H12ClN3O2S
Found 2 metabolite its formula value is C11H12ClN3O2S
(2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDIN-6-YL)METHANOL
(2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDIN-6-YL)METHANOL
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4].