Chemical Formula: C10H14N6O4

Chemical Formula C10H14N6O4

Found 8 metabolite its formula value is C10H14N6O4

2-Aminoadenosine

2,6-Diaminopurine riboside

C10H14N6O4 (282.1076484)


2-Aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

   
   

2,6-diaminopurine arabinoside

2,6-diaminopurine arabinoside

C10H14N6O4 (282.1076484)


   

2-Amino-2-deoxyguanosine

2-Amino-2-deoxyguanosine

C10H14N6O4 (282.1076484)


   

8-Aminoadenosine

8-Aminoadenosine

C10H14N6O4 (282.1076484)


8-Aminoadenosine (8-NH2-Ado), a RNA-directed nucleoside analogue, reduces cellular ATP levels and inhibits mRNA synthesis. 8-Aminoadenosine blocks Akt/mTOR signaling and induces autophagy and apoptosis in a p53-independent manner. 8-Aminoadenosine has antitumor activity[1][2][3]. 8-Aminoadenosine (8-NH2-Ado), a RNA-directed nucleoside analogue, reduces cellular ATP levels and inhibits mRNA synthesis. 8-Aminoadenosine blocks Akt/mTOR signaling and induces autophagy and apoptosis in a p53-independent manner. 8-Aminoadenosine has antitumor activity[1][2][3].

   

2,6-Diaminopurine riboside

2,6-Diaminopurine riboside

C10H14N6O4 (282.1076484)


   
   

3'-Azido-3'-deoxy-5-methylcytidine

3'-Azido-3'-deoxy-5-methylcytidine

C10H14N6O4 (282.1076484)


3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells[1]. 3'-Azido-3'-deoxy-5-methylcytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.